Ecological vulnerability, as an essential analysis technique reflecting regional ecological standing and the diploma of stability, is the important thing content material in international change and sustainable growth. Most research primarily concentrate on modifications of ecological vulnerability in regards to the temporal pattern, however not often take arid and semi-arid areas into consideration to discover the spatial heterogeneity of the ecological vulnerability index (EVI) there. On this research, we chosen the Ningxia Hui Autonomous Area on the Loess Plateau of China, a typical arid and semi-arid space, as a case to analyze the spatial heterogeneity of the EVI each 5 years, from 1990 to 2015. Based mostly on distant sensing information, meteorological information, and financial statistical information, this research first evaluated the temporal‒spatial change of ecological vulnerability within the research space by Geo-information Tupu. Additional, we explored the spatial heterogeneity of the ecological vulnerability utilizing Getis-Ord Gi*. Outcomes present that: (1) the areas with excessive ecological vulnerability are primarily concentrated within the north of the research space, which has excessive ranges of financial progress, whereas the areas with low ecological vulnerability are primarily distributed within the comparatively poor areas within the south of the research space. (2) From 1990 to 2015, ecological vulnerability confirmed an growing pattern within the research space. Moreover, there may be important transformation between completely different grades of the EVI, the place the realm of transformation between a slight vulnerability stage and a lightweight vulnerability stage accounts for 41.56% of the transformation space. (3) Sizzling-spot areas of the EVI are primarily concentrated within the north of the research space, and cold-spot areas are primarily concentrated within the middle and south of the research space. Spatial heterogeneity of ecological vulnerability is important within the central and southern areas however insignificant within the north of the research space. (4) The grassland space is the primary driving issue of the change in ecological vulnerability, which can also be affected by each arid and semi-arid climates and ecological initiatives. This research can present theoretical references for sustainable growth to current possible options on safety measures and administration modes in arid and semi-arid areas.