The United Nations (UN) identifies 4 key components as brokers for change and for addressing societal challenges: schooling, analysis, innovation and management. The usage of know-how, from a pedagogical and organizational viewpoint, in larger schooling establishments has caused new challenges. The mixing of them within the instructing–studying processes has skilled a terrific evolution, giving option to a digital transformation and the acquisition of recent expertise and information, thus pointing in direction of high quality schooling inside the framework of sustainable growth targets. This doc goals to explain and analyze the methods through which seven larger schooling establishments, three in Spain and 4 in Mexico, have taken up the problem of adopting applied sciences and making use of them to the tutorial course of. To this finish, in-depth interviews and direct observations have been carried out. The outcomes level to 3 dimensions: technological, pedagogical and organizational, which make clear the various factors that affect the selection and availability of the usage of applied sciences. The outcomes point out that contextual elements play a determinant function within the potential of an establishment to revenue from applied sciences to assist the tutorial course of and assure its high quality.