The principle goal of the examine was to analyze the results of climatic change on potato yield and yield variability in Agro-Ecological Zones (AEZs) of Iran throughout 2041–2070 (2050s). The Statistical Downscaling Mannequin (SDSM) was carried out on this examine to downscale the outputs of the Common Circulation Mannequin (GCM) and to acquire native local weather projections underneath local weather eventualities for a future interval. The Simply and Pope Manufacturing perform was used to analyze the impacts of climatic change on potato yield. The outcomes confirmed that the results of future climatic change on potato yield and its variability would differ among the many totally different AEZs. Potato yield would change within the vary from −11% to 36% throughout totally different AEZs in the course of the 2050s. Yield variability is anticipated to differ from −29% to six%. Rather more typically, the outcomes indicated that the key potato producing zones would expertise a lower in imply potato yield within the presence of local weather change. Our findings would assist policymakers and planners in designing applicable insurance policies to allocate the lands underneath potato cultivation amongst totally different zones. These outcomes even have necessary implications for adopting ecological zone-specific methods to mitigate the discount in potato yield and meet meals safety.